| # |
Ovr |
Player |
Pts |
Avg |
Yds |
Att |
TD |
Fum Lost |
Yds |
Rec |
TD |
Fum Lost |
Tgt |
Status |
Bye |
| 1. | 1. | Tomlinson, Ladainian SDC RB | 412 | 25.8 | 1815 | 349 | 28 | 2 | 508 | 56 | 3 | 2 | | Athlon/Grogan's | 3 |
| 2. | 2. | Johnson, Larry KCC RB | 321 | 20.1 | 1789 | 416 | 17 | 4 | 410 | 41 | 2 | 4 | | Inside The Stats | 3 |
| 3. | 3. | Gore, Frank SFO RB | 259 | 16.2 | 1695 | 313 | 8 | 12 | 485 | 61 | 1 | 12 | | FFMastermind.com | 7 |
| 4. | 4. | Barber, Tiki FA RB | 232 | 14.5 | 1662 | 327 | 5 | 2 | 465 | 58 | 0 | 2 | | The Huddle | - |
| 5. | 5. | Jackson, Steven STL RB | 318 | 19.9 | 1528 | 346 | 13 | 4 | 806 | 90 | 3 | 4 | | Football Diehards | 7 |
| 6. | 6. | Parker, Willie PIT RB | 257 | 16.1 | 1494 | 337 | 13 | 10 | 233 | 31 | 3 | 10 | | Inside The Stats | 4 |
| 7. | 7. | Johnson, Rudi CIN RB | 200 | 12.5 | 1308 | 341 | 12 | 4 | 124 | 23 | 0 | 4 | | FantasyFootball.com | 5 |
| 8. | 8. | Westbrook, Brian PHI RB | 243 | 16.2 | 1217 | 240 | 7 | 4 | 699 | 77 | 4 | 4 | | FFMastermind.com | 9 |
| 9. | 9. | Taylor, Chester MIN RB | 172 | 11.5 | 1214 | 304 | 6 | 6 | 288 | 42 | 0 | 6 | | Rotoworld | 6 |
| 10. | 10. | Henry, Travis TEN RB | 162 | 11.6 | 1211 | 270 | 7 | 2 | 78 | 18 | 0 | 2 | | Gridiron Grumblings | 7 |
| 11. | 11. | Jones, Thomas CHI RB | 160 | 10.0 | 1205 | 297 | 6 | 2 | 159 | 36 | 0 | 2 | | Gridiron Grumblings | 7 |
| 12. | 12. | James, Edgerrin ARI RB | 161 | 10.1 | 1159 | 337 | 6 | 6 | 217 | 38 | 0 | 6 | | Fantasy Guru | 9 |
| 13. | 13. | Betts, Ladell WAS RB | 176 | 11.0 | 1156 | 245 | 4 | 6 | 445 | 53 | 1 | 6 | | FantasyFootball.com | 8 |
| 14. | 14. | Taylor, Fred JAC RB | 164 | 10.9 | 1146 | 231 | 5 | 4 | 243 | 23 | 1 | 4 | | Draft Sharks | 6 |
| 15. | 15. | Dunn, Warrick ATL RB | 148 | 9.2 | 1140 | 286 | 4 | 0 | 170 | 22 | 1 | 0 | | Fantasy Tailgate | 5 |
| 16. | 16. | Lewis, Jamal BAL RB | 167 | 10.4 | 1132 | 314 | 9 | 4 | 115 | 18 | 0 | 4 | | Fantasy Tailgate | 7 |
| 17. | 17. | Jones, Julius DAL RB | 138 | 8.6 | 1084 | 267 | 4 | 2 | 142 | 9 | 0 | 2 | | Athlon/Grogan's | 3 |
| 18. | 18. | Addai, Joseph IND RB | 176 | 11.0 | 1081 | 226 | 7 | 4 | 325 | 40 | 1 | 4 | | Football Diehards | 6 |
| 19. | 19. | McAllister, Deuce NOS RB | 173 | 11.5 | 1061 | 245 | 11 | 2 | 198 | 30 | 0 | 2 | | Fantasy Guru | 7 |
| 20. | 21. | Green, Ahman GBP RB | 167 | 11.9 | 1059 | 266 | 5 | 4 | 380 | 47 | 1 | 4 | | FantasyBowl.com | 6 |
| 21. | 23. | Bell, Tatum DEN RB | 115 | 8.8 | 1025 | 233 | 2 | 10 | 117 | 24 | 0 | 10 | | Fantasy Guru | 4 |
| 22. | 24. | Brown, Ronnie MIA RB | 150 | 11.5 | 1005 | 242 | 5 | 6 | 282 | 33 | 0 | 6 | | FF Pro Forecast Magazine | 8 |
| 23. | 25. | McGahee, Willis BUF RB | 141 | 10.1 | 990 | 259 | 6 | 4 | 156 | 18 | 0 | 4 | | FantasyBowl.com | 8 |
| 24. | 26. | Jones-Drew, Maurice JAC RB | 213 | 13.3 | 941 | 166 | 13 | 2 | 436 | 46 | 2 | 2 | | FantasyBowl.com | 6 |
| 25. | 27. | Foster, De'shaun CAR RB | 112 | 8.0 | 897 | 227 | 3 | 4 | 159 | 32 | 0 | 4 | | CBS Sportsline | 9 |
| 26. | 28. | Alexander, Shaun SEA RB | 130 | 13.0 | 896 | 252 | 7 | 6 | 48 | 12 | 0 | 6 | | Rotoworld | 5 |
| 27. | 29. | Dillon, Corey NEP RB | 163 | 10.2 | 812 | 199 | 13 | 4 | 147 | 15 | 0 | 4 | | The Huddle | 6 |
| 28. | 30. | Williams, Carnell TBB RB | 95 | 6.8 | 798 | 225 | 1 | 6 | 196 | 30 | 0 | 6 | | CBS Sportsline | 4 |
| 29. | 31. | Droughns, Reuben CLE RB | 108 | 7.7 | 758 | 220 | 4 | 8 | 169 | 27 | 0 | 8 | | Inside The Stats | 6 |
| 30. | 32. | Maroney, Laurence NEP RB | 127 | 9.1 | 745 | 175 | 6 | 2 | 199 | 22 | 1 | 2 | | Draft Sharks | 6 |
